Criteria and requirements for stem cells therapy

1) Autism
2) Male or female gender
3) a) Age from 4 to 15 years for patients who have saved cord blood
b) Age from 6 to 20 years for patients whose umbilical cord blood is not stored
c) Age from 4 to 15 years for patients who have saved the cord blood of a siblings (if HLA matches)

Researches necessary for consultation of the doctor before arrival the patient to the clinic:

  • Consultation of neuropsychologist  and psychiatrist.
  • Consultation of geneticist and results of genetic testing  of  autism (exp.: Syndromic autism gene panel by Centogene (Germany) of equivalent)
  • Consultation of pediatrician
  • Consultation of neurologist
  • Electroencephalography
  • MRI
  • Cytokine profile in serum of patient (IL-1, IL-6, IL-10, IL-13, TNF-alpha)
  • Immunophenotyping of lymphocytes: T4, T8, Treg. NK, NKT, B cells

Special tests for autism assessment:

  1. Vineland Adaptive Behavior Scale – II
  2. Autism Diagnostic Interview – ADI –R (baseline)
  3. ADOS -2 The Autism Diagnostic Observation Schedule
  4. IQ tests: Standford- Binet or Mullen or Wechsler